Ethyl Ascorbic acid

Clinical assessment demonstrated significant improvement with active treatment greater than control for fine wrinkling, tactile roughness, coarse rhytids, skin laxity/tone, sallowness/yellowing, and overall features. Patient questionnaire results demonstrated statistically significant improvement overall, active treatment 84.2% greater than control.

Reference: Arch Otolaryngol Head Neck Surg. 1999 Oct;125(10):1091-8. doi: 10.1001/archotol.125.10.1091.