Retinol (Vitamin A)

Topical retinol improves fine wrinkles associated with natural aging. Significant induction of increased collagen production, retinol-treated aged skin offers greater skin matrix synthesis and improved appearance. Facial wrinkles were reduced by 63.74% at the cheeks and 38.74% in the eye areas after 12 weeks of treatment.

About the clinical trial

Clinical trial was conducted and included subjects between the ages of 35 and 55. A retinol formulation was applied for 12 weeks on the participants. The efficacy and results in improving skin appearance was assessed using digital image-based wrinkle analysis after 12 weeks of retinol application.

Reference: Rong Kong, PhD,1 Yilei Cui, PhD,2 Gary J. Fisher, PhD,2 Xiaojuan Wang, BS,3 Yinbei Chen, MS,3. Journal of Cosmetic Dermatology (2015).