Clinical trials and resources

Clinical Study

87% experienced a reduction in fine lines, wrinkles, puffiness via a blinded clinical assessment. Improvements in skin appearance observed in LED-treated individuals suggested that LED at 660 nm is a safe and effective collagen-enhancement strategy. No adverse events or downtime were reported.

About the clinical trial
Clinical trial was conducted and investigated the potential of light-emitting diode (LED) treatments with a 660 nm. LED effects were then assessed in aged/photoaged individuals in a split-face single-blinded study.

Reference: J Invest Dermatol. 2009 Dec;129(12):2751-9. doi: 10.1038/jid.2009.186. Epub 2009 Jul 9

Dermatol Surg . 2017 Mar;43(3):371-380. doi: 10.1097/DSS.0000000000000981.

Clinical Study

Treated subjects experienced boosted collagen density and significant improvement in skin complexion and feeling

The treated subjects experienced significantly improved skin complexion and skin feeling, profilometrically assessed skin roughness, and ultrasonographically measured collagen density. The blinded clinical evaluation of photographs confirmed significant improvement in the intervention groups compared with the control.

About the clinical trial
A total of 136 volunteers participated in this prospective, randomized, and controlled study. Of these volunteers, 113 subjects were randomly assigned into treatment groups that treated twice a week with 611-660 nm. The data collected at baseline and after 30 sessions included blinded evaluations of clinical photography, ultrasonographic collagen density measurements, computerized digital profilometry, and an assessment of patient satisfaction.

Reference: Photomedicine and Laser Surgery, 28 Nov 2013, 32(2):93-100 DOI: 10.1089/pho.2013.3616 PMID: 24286286 PMCID: PMC3926176

Lasers Med Sci . 2016 Apr;31(3):531-8. doi: 10.1007/s10103-016-1888-9. Epub 2016 Feb 12.

Lasers Med Sci . 2020 Feb;35(1):157-164. doi: 10.1007/s10103-019-02812-6. Epub 2019 Jun 5.

Clinical Study

Assessed the efficacy of the combination of Microcurrent and near-infrared (IR) LED therapy for moderate acne and wrinkles.

Improvement ranging from 0% to 83.3%. A downward shift in the Burton grade was seen overall. Non-inflammatory lesion counts increased in four patients, but improved in the other seven by an average of 48.8%. No adverse effects were reported.

About the clinical trial
Clinical trial was conducted with male and female subjects with acne grades at baseline ranging from Burton grade 1 to 5. Subjects were treated with LED therapy and Microcurrent. No other treatment was allowed. Results were assessed and compared with the baseline values at 1, 4 and 8 weeks post-treatment.

Reference: J Cosmet Laser Ther. 2009 Jun;11(2):125-8. doi: 10.1080/14764170902777349.

Mil Med Res . 2014 Nov 24;1:24. doi: 10.1186/2054-9369-1-24. eCollection 2014.

Acta Mech Sin . 2021;37(12):1843-1871. doi: 10.1007/s10409-020-01026-2. Epub 2021 Feb 6.